The Malvern NanoSight utilizes Nanoparticle Tracking Analysis (NTA) to characterize nanoparticles from 30-800nm in solution. Each particle is individually but simultaneously analyzed by direct observation and measurement of diffusion events. This particle-by-particle methodology produces high resolution results for particle size distribution and concentration, while visual validation provides users with additional confidence in their data. Both particle size and concentration are measured, while a fluorescence mode provides differentiation of labelled or naturally fluorescing particles.
Measurement options available:
- Size analysis (20-800nm)
- Particle concentration (10^6-10^9 particles/mL)
- Temperature range 20-50C
- Sample volume required: ~1mL
- 532nm laser available for fluorescence measurements
Instrument protocols in the "downloads" menu to the right.